In 2009, Children’s Hospital of UPMC (Children’s) moved into a LEED-certified facility in the Lawrenceville neighborhood of Pittsburgh, PA, demolishing the existing hospital, constructed on the Oakland site in 1926.  Researchers at the University of Pittsburgh partnered with Children’s in 2006 to conduct a comparative longitudinal assessment of the two hospitals to determine the effects of holistic and sustainable hospital design.  This study statistically compares metrics of expenses, productivity, quality of care, staff satisfaction, and utilities between the old hospital and the new, LEED-certified hospital.  Results show no significant statistical difference in Children’s total expenditures, a 10% increase in staff direct care hours, a 5% increase in employee tenure, and a 25-50% drop in turnover and position vacancies in the new LEED-certified facility. Additionally, despite a 300% increase in square footage of the hospital and updates to hospital performance in relation to building codes, utility consumption rates for electricity, water, and gas have actually decreased by nearly 60% per square foot.